Graduate Students:

Rivkah Rogawski

2011: Ph.D. student at Columbia University

2007-2011: B.A. in Chemistry, Yeshiva University’s Stern College for Women, USA

rtr2119@columbia.edu

My research focuses on developing methods for the study of membrane proteins thanks to dynamic nuclear polarization. Right now I am working on KcsA, a model potassium channel, and learning about molecular biology, protein expression and solid-state NMR.

Yunyao Xu

2012: Ph.D. student at Columbia University

2009-2011: B.S. in Chemistry, Hunan University, China

2007-2009: Certificate, Li Da Honored Class, Hunan University, China

yx2218@columbia.edu

My research mainly focuses on exploring transition between various states of KcsA,a potsassium channel, specially for the C-type inactivation process and further illustrate the allostery involved in the gating mechanism using solid state NMR.

Gary S. Howarth

2014: Ph.D. student at Columbia University

2010 – 2013: Science Teacher, Academy of the Sacred Heart

2007 – 2010: Science Teacher, New Orleans Charter Science and Math High School

2006 – 2007: Research Associate, Sterilex Corporation

2002 – 2006: B.A., Chemistry, Lewis & Clark College

gary@gshowarth.com

My research examines the interactions of membrane ion channels with their lipid contacts, exploring the way in which lipid composition affects structure and function of membrane proteins using biochemistry and NMR. To that end, I am developing novel technique to probe coordinated lipid-protein dynamics.

Dongyu(Allison) Zhang

2011-2013 University of Wisconsin Madison

2014-present: PhD student at Columbia University

dz2282@columbia.edu

Reseach Interest: my research focus on the effect of different lipid compositions on the structure and allosteric coupling of potassium channel, KcsA.

Kelsey McCoy

2014: PhD student at Columbia University

2010-2014: B.S. in Chemistry from the University of Minnesota, Twin Cities

kmm2286@columbia.edu

My research is focused on developing robust in cell DNP techniques and extending the biological relevance of traditional ssNMR techniques. I am interested in the bacterial cytoskeleton, with a specific focus on the structure and mechanism of the Z ring and FtsZ polymerization dynamics.

Undergraduate Students:

John Philippe Avendano

Columbia College ’18

jpa2140@columbia.edu

My research focuses on the analysis of radical stability for the purposes of DNP, which boosts NMR signal intensity using the unpaired electrons in radicals. I analyze the reduction rates of several radicals combined with specific reducing agents via EPR Spectroscopy, in addition to UV Vis Spectrometry to see which radicals produce the strongest signals for NMR. I have recently undertaken pursuing a project testing various c1oncentrations of NEM (N-Ethylmaleimide) to be added to radicals for maximum preservation and cell survival. Previous studies hinted towards N-ethylmaleimide’s (NEM) dual ability to preserve radical signals in whole cell cultures; yet it has also been shown to be cytotoxic, meaning it kills off cells. Finding the ideal concentration with which to treat cells could yield a solution that helps preserve finite radical lifetimes, aiding the McDermott Group’s ability to enhance solid state NMR signals.

Lia Parkin

Barnard College

lap2184@columbia.edu

My research focuses on investigating liposomes, which have been used by other group members to study KcsA, a membrane channel protein. I have been characterizing liposomes and their degradation using solution NMR. I am going to expand my studies to explore KcsA and to determine whether the liposome system mimics the natural environment of Streptomyces lividans (the organism that KcsA comes from) closely enough. 

Alumni:

Dr. Ségolène Laage          Email

Noah Chodos                 Email --Albert Einstein Medical School  

Sonya Li                   Email    

Dr. Ivan Sergeyev      -- Bruker

Dr. Benjamin Wylie                                 -- Texas Tech University

Dr. Caitlin Quinn                    Email        -- University of Delaware           

Dr. Wenbo Li                         Email        -- Johns Hopkins University School of Medicine

Claribel Nunez                       Email        -- University of Florida

Dr. Manasi Bhate                   Website    -- University of California, San Fransisco

Salima Bahri                                           -- Massachusetts Institute of Technology

Dr. Jackie Catalano                                -- Metropolitan Museum of Arts

Dr. Penny Kuoying Huang

Dr. Ansgar Siemer                 Website    -- University of Southern California

Dr. Simone Gieschler            Email

Dr. Yimin Xu                                            -- Pacific Northwest National Laboratory

Dr. Yisong Tao                      Website     -- Albert Einstein College of Medicine

Dr. Matthew Craddock          Website     -- Millennium High School

Dr. Lin Tian

Dr. Mike Harris                      Email         -- University of Massachusetts

Dr. Amir Goldbourt                Website     -- Tel Aviv University

Dr. Justin Lorieau                  Website     -- University of Illinois at Chicago

Dr. Lei Huang                        Email         -- Fudan University

Dr. Krisztina Varga                Website     -- University of Wyoming

Dr. Tijana Jovanovic              Website     -- Lippincott-Schwarz Lab NIH

Dr. Nicholas Breen                Email         -- Bruker Biospin

Dr. Benjamin Gross               Email         -- Strategic Business Insights

Dr. Stephan Zech                                    -- ARIAD Pharmaceuticals

Dr. Tatyana Igumenova         Website     -- Texas A&M University

Dr. Sharon Rozovsky             Website     -- University of Delaware

Dr. Chad Rienstra                  Website     -- UIUC

Dr. Lane Gilchrist                   Website     -- City College New York

Dr. Anja Böckmann                Website     -- IBCP

Dr. Michelle Mac Brooks        Website     -- Univeristy of Maryland

Dr. Xiangjin Song                                     -- Water Corporation

Dr. Alexey Peshkovsky                            -- Industrial Sonomechanics

Dr. Lorenz Mitschang             Email         -- PTB

Dr. Hyerim Lee                                         -- Merck

Dr. Daron Standley                Website     -- Osaka University

Dr. Yufeng Wei                      Website     -- Rockefeller University & Seton Hall University

Dr. Tatyana Polenova            Website     -- University of Delaware

Dr. Martin Zysmillich              Website     -- George Washington Univeristy

Dr. Zhengtian Gu                                     -- Theravance Inc.

Dr. York Tomita                     Website      -- Georgetown University

Dr. John Williams                  Website      -- City of Hope

Dr. Kai Liu